chidziwitso

Titaniyamu aloyi asintha gawo la ma implants ndi zida zamankhwala chifukwa cha mawonekedwe ake apadera. Mwa izi, Ti-6Al-7Nb yatuluka ngati chisankho chokondedwa pamapulogalamu ambiri azachipatala. Aloyi iyi, yopangidwa ndi titaniyamu yokhala ndi 6% aluminiyamu ndi 7% niobium, imapereka kuphatikiza kwapadera kwamphamvu, kuyanjana kwachilengedwe, komanso kukana dzimbiri zomwe zimapangitsa kuti zikhale zoyenera kugwiritsidwa ntchito m'thupi la munthu. Mu positi iyi yabulogu, tiwona chifukwa chake Ti-6Al-7Nb yakhala chinthu chofunikira kwambiri pazachipatala komanso momwe ikufananira ndi ma aloyi ena.

Ndi zinthu ziti zazikulu za Ti-6Al-7Nb zomwe zimapangitsa kuti zikhale zoyenera kuyika zachipatala?

Ti-6Al-7Nb ili ndi zida zochititsa chidwi zomwe zimapangitsa kuti ikhale yoyenera kwambiri pama implants ndi zida zamankhwala. Choyamba, biocompatibility yake yabwino kwambiri ndiye chinthu chofunikira kwambiri pakukhazikitsidwa kwake. Thupi la munthu nthawi zambiri limalekerera bwino aloyiyi, popanda chiopsezo chochepa cha kukhumudwa kapena kukanidwa. Izi biocompatibility zimachokera ku mapangidwe khola okusayidi wosanjikiza pamwamba pa aloyi, amene amakhala ngati chotchinga pakati implant ndi zozungulira.

Katundu wina wofunikira wa Ti-6Al-7Nb ndi kuchuluka kwake kwamphamvu ndi kulemera kwake. Alloy iyi imapereka mphamvu zolimba kwambiri komanso kukana kutopa pomwe zimakhala zopepuka. Pazachipatala, izi zikutanthauza kuti ma implants ndi zida zopangidwa kuchokera ku Ti-6Al-7Nb zimatha kupirira zovuta zomwe zimagwiritsidwa ntchito tsiku ndi tsiku popanda kuwonjezera kulemera kosafunikira kwa thupi la wodwalayo. Izi ndizofunikira makamaka pazamankhwala a mafupa, pomwe implant iyenera kunyamula katundu wambiri ndikusunga bata kwanthawi yayitali.

Kukana kwa dzimbiri ndi chinthu china chofunikira kwambiri cha Ti-6Al-7Nb. Thupi laumunthu limapereka malo ovuta kwa ma implants, okhala ndi madzi osiyanasiyana am'thupi ndi njira zama mankhwala zomwe zimatha kuwononga zinthu pakapita nthawi. Ti-6Al-7Nb imawonetsa kukana kwambiri kwa dzimbiri, chifukwa cha gawo lina la chitetezo cha oxide wosanjikiza chomwe chimapanga pamwamba pake. Kukaniza kumeneku kumathandizira kuonetsetsa kuti ma implants atalikirapo komanso amachepetsa chiopsezo cha ayoni achitsulo kulowa m'magulu ozungulira.

Aloyi imasonyezanso zinthu zabwino za osseointegration, zomwe zimatha kupanga mgwirizano wolimba ndi fupa la mafupa. Makhalidwewa ndi ofunikira kwa ma implants a mafupa, chifukwa amalimbikitsa kukhazikika kokhazikika komanso kupambana kwa nthawi yaitali kwa implant. Pamwamba pa Ti-6Al-7Nb chitha kusinthidwa kudzera mumankhwala osiyanasiyana kuti apititse patsogolo luso la osseointegration, ndikupangitsa kuti ikhale chisankho chosunthika pamagwiritsidwe osiyanasiyana a mafupa.

Komanso, Ti-6Al-7Nb ili ndi zotanuka modulus yotsika poyerekeza ndi zida zina zachitsulo. Katunduyu amathandizira kuchepetsa chiwopsezo choteteza kupsinjika, chodabwitsa pomwe implant imanyamula katundu wambiri, zomwe zimapangitsa kuti mafupa asungunuke mozungulira. Pofananiza kwambiri ndi zotanuka modulus ya fupa, ma implants a Ti-6Al-7Nb amatha kulimbikitsa kugawa bwino katundu ndikusunga thanzi la mafupa m'magulu ozungulira.

Kukula kwamafuta a Ti-6Al-7Nb kumagwirizananso ndi mafupa amunthu, omwe ndi opindulitsa pakukhazikika kwa nthawi yayitali. Kufanana kumeneku pakukulitsa matenthedwe kumathandiza kuchepetsa kupsinjika kwa mawonekedwe a fupa-implant panthawi yakusintha kwa kutentha, zomwe zimathandizira kuti mphirayo ikhale yopambana komanso yolimba.

Kodi Ti-6Al-7Nb ikufananiza bwanji ndi ma aloyi ena a titaniyamu pamagwiritsidwe azachipatala?

Poyerekeza Ti-6Al-7Nb ndi ma aloyi ena a titaniyamu omwe amagwiritsidwa ntchito pazachipatala, pali zinthu zingapo zomwe zimachitika. Kuyerekezera kumodzi kofala ndi Ti-6Al-4V, yomwe yakhala yodziwika bwino m'makampani azachipatala kwa zaka zambiri. Ngakhale ma aloyi onsewa amapereka zinthu zabwino kwambiri, Ti-6Al-7Nb ili ndi zabwino zina zomwe zapangitsa kuti ichuluke.

Chinthu chimodzi chosiyana kwambiri ndi momwe ma aloyi amapangidwira. Ti-6Al-7Nb imalowa m'malo mwa vanadium yomwe imapezeka mu Ti-6Al-4V ndi niobium. Kulowetsedwa uku kumayang'ana zovuta zomwe zingachitike kwa nthawi yayitali za vanadium m'thupi. Ngakhale kuopsa kokhudzana ndi vanadium nthawi zambiri kumawoneka ngati kotsika, kugwiritsa ntchito niobium mu Ti-6Al-7Nb kumathetseratu nkhawayi, ndikupangitsa kuti ikhale njira yabwino yopangira ma implants a nthawi yayitali.

Pankhani yamakina, Ti-6Al-7Nb imawonetsa mphamvu zofananira ndi Ti-6Al-4V, ndipo kafukufuku wina akuwonetsa kukana kutopa pang'ono. Izi zimapangitsa Ti-6Al-7Nb kukhala yoyeneranso pamapulogalamu onyamula katundu pomwe ikupereka ntchito yabwino kwanthawi yayitali. Mbiri zofananira zamphamvu zimatanthauza kuti mapangidwe omwe alipo a zida zamankhwala ndi ma implants amatha kusinthidwa mosavuta kuchokera ku Ti-6Al-4V kupita ku Ti-6Al-7Nb popanda kusintha kwakukulu.

Biocompatibility ndi gawo lina lomwe Ti-6Al-7Nb kuwala. Ngakhale kuti ma alloys onsewa amawonedwa kuti ndi ogwirizana kwambiri, kafukufuku wina akuwonetsa kuti Ti-6Al-7Nb ikhoza kukhala ndi malire pang'ono potengera kuyankha kwa ma cell ndi kuphatikiza kwa minofu. Izi zitha kumasulira kuti zigwire bwino ntchito mu vivo, makamaka pamapulogalamu omwe amafunikira kulumikizana kwapafupa kapena kuphatikiza minofu yofewa.

Poyerekeza ndi titaniyamu yoyera yamalonda (CP-Ti), yomwe imagwiritsidwanso ntchito pazinthu zina zamankhwala, Ti-6Al-7Nb imapereka mphamvu zapamwamba kwambiri komanso kukana kuvala bwino. Izi zimapangitsa Ti-6Al-7Nb kukhala yoyenera kwa mapulogalamu omwe amafunikira makina apamwamba kwambiri, monga olowa m'malo olowa kapena ma implants a mano. Komabe, CP-Ti imakhalabe chisankho chabwino pamapulogalamu omwe mphamvu zomaliza ndizosafunikira kwambiri, komanso kuti biocompatibility yayikulu ikufunika.

Ndizofunikira kudziwa kuti ngakhale Ti-6Al-7Nb ili ndi zabwino zambiri, mwina sikungakhale chisankho chabwino pazachipatala chilichonse. Mwachitsanzo, ngati kukana dzimbiri kumafunika, monga pamtima, ma aloyi ena monga Nitinol (nickel-titanium alloy) angakonde. Momwemonso, pazinthu zina zamano, zirconia za ceramic zitha kusankhidwa chifukwa cha kukongola kwawo.

Kusankha pakati pa Ti-6Al-7Nb ndi ma aloyi ena nthawi zambiri kumabwera kuzomwe zimafunikira pakugwiritsa ntchito, kuphatikiza zosowa zamakina, kulingalira kwa biocompatibility, ndi njira zopangira. Komabe, kuchuluka kwazinthu zoperekedwa ndi Ti-6Al-7Nb kumapangitsa kukhala chisankho chosunthika komanso chodziwika bwino pamagwiritsidwe osiyanasiyana azachipatala.

Kodi ntchito zoyamba zachipatala za Ti-6Al-7Nb ndi ziti, ndipo chifukwa chiyani zimasankhidwira ntchito izi?

Ti-6Al-7Nb imapeza ntchito pazida zosiyanasiyana zamankhwala ndi zoyikapo, chifukwa cha kuphatikiza kwake kwapadera. Kumvetsetsa ntchitozi komanso zifukwa zomwe zimasankhidwira kungapereke chidziwitso cha kusinthasintha komanso kufunikira kwa alloy iyi mumankhwala amakono.

Chimodzi mwazofunikira kwambiri za Ti-6Al-7Nb ndi ma implants a mafupa, makamaka m'malo olowa m'malo monga ma prostheses a chiuno ndi mawondo. Kuchuluka kwa mphamvu ya alloy-to-weight ratio kumapangitsa kukhala koyenera kwa izi zonyamula katundu, pomwe implant iyenera kupirira mphamvu zazikulu kwazaka zambiri. The low elastic modulus ya Ti-6Al-7Nb, yomwe ili pafupi kwambiri ndi mafupa poyerekeza ndi zipangizo zina zambiri zazitsulo zopangira zitsulo, zimathandiza kuchepetsa kupsinjika maganizo ndikulimbikitsa thanzi labwino la mafupa a nthawi yayitali pafupi ndi implant.

Pankhani ya implants zamano, Ti-6Al-7Nb yapeza chidwi kwambiri. Kuyika kwa mano kumafunikira zinthu zomwe zimatha kulumikizana bwino ndi fupa (osseointegration) pomwe zimalimbana ndi malo owopsa amkamwa komanso kupsinjika kwamakina akutafuna. Ti-6Al-7Nb imakwaniritsa zofunikira izi modabwitsa. Biocompatibility yake yabwino kwambiri imalimbikitsa kukula kwa maselo a mafupa pamtunda, kuonetsetsa kugwirizana kwamphamvu ndi kosatha pakati pa implant ndi nsagwada. Kukana kwa dzimbiri kwa aloyi ndikofunikira kwambiri m'malo amkamwa, pomwe malovu ndi tinthu tating'onoting'ono tazakudya zimatha kuyambitsa zovuta pakuyika zida.

Kuyika kwa msana kumayimira malo ena omwe Ti-6Al-7Nb amapambana. Ma implants awa, omwe amaphatikizapo kusintha kwa ma vertebral body, ma interbody fusion cages, ndi zomangira za pedicle, amayenera kusunga umphumphu wawo pansi pamikhalidwe yovuta kwambiri pomwe akulimbikitsa kukula kwa mafupa ndi kuphatikiza. Kutopa kwakukulu kwamphamvu Ti-6Al-7Nb imapangitsa kuti ikhale yoyenera pakugwiritsa ntchito izi, pomwe kutsitsa kwapang'onopang'ono kungayambitse kulephera kwa implant ngati sikuyankhidwa bwino. Kuphatikiza apo, kuthekera kopanga ma porous okhala ndi Ti-6Al-7Nb kudzera munjira zapamwamba zopangira monga kusindikiza kwa 3D kumathandizira ma implants omwe amatsanzira bwino momwe mafupa achilengedwe amapangidwira, kupititsa patsogolo kuphatikizika kwa osseointegration.

M'malo opangira ma trauma fixation, monga mbale za mafupa ndi zomangira, Ti-6Al-7Nb imapereka zabwino zingapo. Mphamvu zake zimalola kupanga zida zotsika kwambiri zomwe zimapereka kukhazikika kolimba popanda kuchulukirachulukira. Izi ndizopindulitsa makamaka m'madera omwe ali ndi minofu yofewa yochepa, monga opaleshoni ya craniomaxillofacial. Biocompatibility ya Ti-6Al-7Nb ndiyofunikiranso pamapulogalamuwa, chifukwa zidazi nthawi zambiri zimakhala m'thupi kwa nthawi yayitali komanso nthawi zonse.

Ntchito zamtima, ngakhale kuti ndizochepa kwambiri kuposa zogwiritsira ntchito mafupa, zimapindulanso ndi katundu wa Ti-6Al-7Nb. Alloy angagwiritsidwe ntchito pazigawo za valavu ya mtima ndi mbali za mapampu amtima opangira. M'mapulogalamuwa, kukana kutopa kwambiri kwazinthuzo komanso kuyanjana kwachilengedwe ndikofunikira, chifukwa zidazi zimayenera kugwira ntchito mosalakwitsa pamizere mamiliyoni ambiri m'malo ovuta kwambiri amtima.

Kusankhidwa kwa Ti-6Al-7Nb ntchito zosiyanasiyana zamankhwala izi zimayendetsedwa ndi zinthu zingapo. Choyambirira komanso chofunikira kwambiri ndi biocompatibility yake, yomwe imachepetsa chiopsezo cha zotsatira zoyipa ndikulimbikitsa kulumikizana bwino ndi minofu ya thupi. Zochita zamakina za alloy, kuphatikiza mphamvu zake zambiri, kuchepa kwapang'onopang'ono, komanso kukana kutopa, zimapangitsa kuti zikhale zoyenera pamitundu yambiri yonyamula katundu. Kulimbana ndi dzimbiri kwa Ti-6Al-7Nb ndikofunikira kwambiri m'chilengedwe, pomwe ma implants amakumana ndi madzi am'thupi komanso momwe angagwiritsire ntchito electrochemical.

Chinthu chinanso chomwe chimapangitsa kuti Ti-6Al-7Nb asankhidwe ndikusinthasintha kwake pakupanga njira. Alloy imatha kuponyedwa, kupangidwa, kapena kupangidwa pogwiritsa ntchito njira wamba, zomwe zimapangitsa kuti pakhale mawonekedwe ovuta komanso mawonekedwe. Posachedwapa, kuyanjana kwa Ti-6Al-7Nb ndi njira zopangira zowonjezera kwatsegula mwayi watsopano wopanga ma implants okhazikika, okhazikika a odwala okhala ndi ma geometri okhathamiritsa komanso ma porous omwe amalimbikitsa kukula kwa minofu.

Kuchita kwa nthawi yayitali kwa ma implants a Ti-6Al-7Nb ndichinthu chinanso chofunikira. Kukhazikika kwa aloyi m'thupi, kuphatikiza ndi kukana kwake kuvala ndi dzimbiri, kumathandizira kuti ma implants azikhala ndi moyo wautali. Izi ndizofunikira makamaka kwa anthu okalamba, pomwe kulimba kwa implants zachipatala kumatha kukhudza kwambiri moyo komanso kuchepetsa kufunika kokonzanso maopaleshoni.

Pomaliza, Ti-6Al-7Nb yadzikhazikitsa yokha ngati chinthu chokondedwa pazamankhwala osiyanasiyana chifukwa cha kuphatikiza kwake kwapadera kwa biocompatibility, ma mechanical properties, ndi processability. Kuchokera ku ma implants onyamula mafupa onyamula katundu kupita kumalo opangira mano ndi zida zowongolera zoopsa, alloy iyi ikupitilizabe kugwira ntchito yofunika kwambiri pakupititsa patsogolo ukadaulo wazachipatala ndikuwongolera zotsatira za odwala. Pamene kafukufuku ndi chitukuko mu biomaterials zikupitirira, Ti-6Al-7Nb ikuyenera kukhala patsogolo pakuyika zida zachipatala, ndikuwongolera mosalekeza pamapangidwe, kukonza, ndi machiritso apamwamba kupititsa patsogolo ntchito yake ndikukulitsa ntchito zake m'zachipatala.

Ku SHAANXI CXMET TECHNOLOGY CO., LTD, timanyadira zamitundu yathu yayikulu, yomwe imathandizira zosowa zosiyanasiyana zamakasitomala. Kampani yathu ili ndi luso lapadera lopanga ndi kukonza, kuwonetsetsa kuti zinthu zathu ndi zapamwamba komanso zolondola. Ndife odzipereka pazatsopano ndipo timayesetsa mosalekeza kupanga zinthu zatsopano, kutipangitsa kukhala patsogolo pamakampani athu. Ndi luso lotsogola laukadaulo, timatha kusintha ndikusintha msika womwe ukusintha mwachangu. Kuphatikiza apo, timapereka mayankho osinthika kuti akwaniritse zofunikira zamakasitomala athu. Ngati muli ndi chidwi ndi zinthu zathu kapena mukufuna kudziwa zambiri zazomwe timapereka, chonde musazengereze kutilankhula nafe pa sales@cxmet.com. Gulu lathu limakhala lokonzeka nthawi zonse kukuthandizani.

Zothandizira:

1. Geetha, M., Singh, AK, Asokamani, R., & Gogia, AK (2009). Ti based biomaterials, chisankho chomaliza cha ma implants a mafupa - Ndemanga. Kupita patsogolo kwa Sayansi Yazinthu, 54 (3), 397-425.

2. Niinomi, M. (2008). Mechanical biocompatibilities ya titaniyamu aloyi pazogwiritsa ntchito zamankhwala. Journal of the Mechanical Behavior of Biomedical Materials, 1 (1), 30-42.

3. Sidambe, AT (2014). Biocompatibility ya ma implants apamwamba opangidwa ndi titaniyamu - Ndemanga. Zida, 7(12), 8168-8188.

4. Chen, Q., & Thouas, GA (2015). Metallic implant biomatadium. Zakuthupi Sayansi ndi Zomangamanga: R: Malipoti, 87, 1-57.

5. Cui, C., Liu, H., Li, Y., Sun, J., Wang, R., Liu, S., & Greer, AL (2005). Kupanga ndi kuyanjana kwachilengedwe kwa nano-TiO2/titanium alloys biomaterials. Makalata a Zida, 59 (24-25), 3144-3148.

6. Okazaki, Y., & Gotoh, E. (2005). Kuyerekeza kutulutsidwa kwachitsulo kuchokera kumitundu yosiyanasiyana yazitsulo mu vitro. Zamoyo, 26(1), 11-21.

7. Rack, HJ, & Qazi, JI (2006). Titaniyamu aloyi kwa biomedical ntchito. Zakuthupi Sayansi ndi Umisiri: C, 26 (8), 1269-1277.

8. Wang, K. (1996). Kugwiritsa ntchito titaniyamu pazachipatala ku USA. Zakuthupi Sayansi ndi Umisiri: A, 213(1-2), 134-137.

9. Long, M., & Rack, HJ (1998). Ma aloyi a Titaniyamu m'malo olowa m'malo onse - mawonekedwe asayansi azinthu. Zamoyo, 19(18), 1621-1639.

10. Elias, CN, Lima, JHC, Valiev, R., & Meyers, MA (2008). Kugwiritsa ntchito kwachilengedwe kwa titaniyamu ndi ma aloyi ake. JOM, 60(3), 46-49.